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The developers behind Solana-based memecoin BONK burned their allocation of 5 trillion BONK tokens early Friday in a bid to stem the token’s bearish momentum.

After the token burn event, which saw nearly $1 million worth of BONK taken out of circulation, BONK’s circulating supply shrank 5% to 94.16 trillion, according to data from Solana block explorer Solscan .

$BONK represents the best of Solana. Our community works together across the ecosystem to bring about positive change for all of us.

The 5 trillion $BONK Tokens assigned to “The Team” were burned. pic.twitter.com/g7w62sdKhb

– Good! (@bonk_inu) January 5, 2023

A token burn is a standard process to reduce the supply of a cryptocurrency, which, the theory goes, can lead to an increase in the asset’s prices.

But BONK reacted differently.

The BONK price decline continues

At the time of the token burn, each BONK token was changing hands for around $0.00000244, according to data from CoinGecko. Since then, the token has lost around 12% in value and is trading at $0.00000192 as of this writing.

In the last 24 hours, BONK has lost almost 50% of its value, despite the development team’s token burn.

However, this pales in comparison to the meme coin’s weekly performance, which has seen BONK up 2,015%. BONK’s performance also lifted Solana, which is up about 35% over the week (although it’s down about 2% over the past 24 hours).

Heavy user activity

Despite its short-term negative price action, BONK has seen strong growth in user activity over the past week.

According to data from Dune Analytics, BONK has seen over 4 million transactions in the last three days, a number that is slightly higher than the total number of transactions processed by the Ethereum blockchain over the same period.

The token has also seen an increase in its daily active users (DAU) over the past week. Almost 15,000 users have interacted with the token over the past three days.

Daily active users is a measure to track user activity associated with a DApp or cryptocurrency. The higher the value, the more interest in the token there is on the market.

Chart showing the daily growth of active users of BONK. Source: Dune Analytics.

As of this writing, more than 103,759 wallet addresses hold BONK tokens, a number that is up 99.9% since December 25, 2022, according to data from Solscan.

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For his very first documentary experience, Dominic Arpin is interested in endurance sports – which can also be described as extreme – but above all in the people who practice them.

In a reduced formation, the film team, consisting of director Jérôme Pinette, cameraman Martin Boufard and Dominic Arprin himself, traveled to all corners of the world to shoot the series “Les crinqués”, which will be released on Escape these days.

The boys went to the United States to follow cyclist Sébastien Sasseville as he crossed the country for the Race Across America, and then to Thailand to follow Bruno Blanchet, a keen runner. She also followed high jumper Lysanne Richard, who is preparing for one of the toughest jumps of her career while recovering from an injury, and Charlotte Levasseur-Paquin, a Gaspésie, on the GR A1 – probably Quebec’s most difficult race – in autonomy .

Both beautiful and captivating, the series unfolds in a very neat aesthetic that lets the postcard landscapes shine through. The viewer thus becomes a direct witness of the preparation of these super athletes – ordinary people who have nothing superhuman but have given themselves the means of their ambitions. “We wanted to make a beautiful show, something that’s both pleasing to the eye, but also nourishes the soul a little and lets us understand what’s behind the human being,” emphasized the presenter in an interview with QMI agency during the recovery from a virus.

The film crew wasn’t afraid to mobilize to get the perfect shot, even going so far as to walk 25km of steep trails with all their gear on their backs.

A whole scare in Mexico

The documentary begins in the Mexican state of Chihuahua, where the “Crinqués” team followed Isabelle Bernier and husband and wife team Joan Roch and Anne Genest in the Ultra Run Raramuri, a 190km race through gorges with 10,000m of elevation gain.

PHOTO COUR TESY Quebecor Content

The expedition takes place in a barren desert where some of the trails are in drug cartel territory. Getting up at dawn to take some shots in the rising sun, the film crew had quite a scare when they were apprehended by the Mexican army, who followed them in a helicopter.

“The day before there was an attack on a member of the government and the army was on its feet. A helicopter, a Griffon, flew overhead, then came back and started circling around us. Eventually he ended up in the “parking lot” where we were parked and we had to walk towards them slowly with our hands on our heads – the soldiers were armed with machine guns. We got our interpreter because nobody spoke Spanish very well and he explained to them that we were there for a shoot,” explained Dominic Arpin.

“I can tell you that we really had the bitch that day. It was our first stint of shooting and I imagined ending up in prison in Mexico. It was the most stressful moment of the series,” he admitted.

Dominic Arpin, who runs TVA’s Vlog, has long dreamed of making a documentary. “I’ve been telling myself all the time that I’m not ready, that I don’t have the right subject, but the stars were there and it’s a subject that I’m still good at. These are also athletes that I’ve been following for a long time and I’m also very interested in this question,” says the host, who already has a list of names for a possible second part of this series in mind.

The program “Les crinqués” is broadcast on Thursdays at 8 p.m. on Évasion.

The very first patient treated with a new, gene-edited stem cell therapy developed for sickle cell disease suffered a serious side effect that forced the drugmaker to halt the study.

Graphite Bio said it voluntarily withheld further dosing in the Phase I/II CEDAR study after concluding that the serious adverse event was likely related to its therapy, Nula-Beglogene Autogedtemcel (Nula-Cel). It also reported the event to the FDA.

In particular, the patient who was dosed in August saw persistently low blood cell counts or pancytopenia “which required continuous transfusion and growth factor support.”

“The patient remains enrolled in the CEDAR study and will continue to be cared for and closely monitored by the clinical investigator and study staff,” a spokesperson wrote in response to a query from Endpoints News. “We are in close contact with the clinical site and are monitoring the patient’s condition. Out of respect for patient privacy, no further details about the patient can be released at this time.”

While the study is suspended, Graphite Bio is thoroughly investigating the adverse event, analyzing risk factors and mitigation strategies – with changes to the Nula-Cel manufacturing process also on the table.

“The company’s initial investigation ruled out common causes of post-transplant pancytopenia such as viral infection and autoimmunity, leading to the conclusion that it likely results from the Nula-Cel treatment itself,” wrote Cowen analyst Phil Nadeau after one Conversation with the manager

Several other companies have set out to treat sickle cell disease — which is caused by defective red blood cells and is characterized by painful episodes — using the same approach of editing genes in stem cells and then putting them back into the patient. But while Vertex/CRISPR and Editas try to solve the problem by activating a fetal hemoglobin gene in cells, Graphite Bio’s idea is to correct adult mutated hemoglobin with its own set of CRISPR-inspired tools developed by academic pioneers such as Maria Grazia Roncarolo and Matthäus Porteus.

“At the DNA level, we’re making stem cells normal again,” CEO Josh Lehrer described the approach back in 2021.

SVB Securities’ Mani Foroohar wrote that the company is now investigating whether this basic approach could have caused the side effect. Other hypotheses include “the quality of the patients’ underlying bone marrow,” Graphite’s technology, and the use of AAV6 as a delivery vector.

“Given this number of degrees of freedom in any assessment, determining the right remedy with a high enough degree of confidence to drive a patient’s return to treatment will be a lengthy and uncertain process,” he wrote.

While the company had previously hoped to have proof-of-concept data from 15 patients by mid-2023, it’s now pushing that schedule back.

Editor’s Note: Updated to include comment from Graphite Bio.

Aurich Lawson | Getty Images

The start of the new year means the start of a new EV tax incentive in the US. Previously, the IRS allowed taxpayers to claim a tax credit of up to $7,500 for a new plug-in vehicle, with the exact amount determined by the battery’s capacity in kWh. Additionally, the credit was designed to end once a manufacturer sold its 200,000th plug-in, though only Tesla and General Motors have ever reached that milestone.

But the Inflation Reduction Act (IRA) of 2022 rewrote tax incentives for plug-in vehicles, and the new rules went into effect in early January. Now the tax credit applies to “clean vehicles” rather than plug-ins, and covers fuel cell electric vehicles, some plug-in hybrid electric vehicles and all battery electric vehicles.

However, it is now a more complex animal. The maximum tax credit is still $7,500, but to qualify, a vehicle must have a battery capacity of at least 7 kWh, a gross vehicle weight of less than 14,000 pounds, and be fully assembled in North America. There are price caps – vans, SUVs and pickups can’t cost more than $80,000, and other vehicles must stay under $55,000 to qualify. There are also income caps: $300,000 for married couples filing jointly, $225,000 for heads of household, and $150,000 for other taxpayers.

And as before, it’s a tax credit, meaning you must have at least as much tax liability as the credit during the year the car was purchased. If your total federal tax liability for the year is less than $7,500, you can claim only as much credit as that liability.

There are also commercial clean vehicle tax credits, used clean vehicle tax credits, and leased vehicle tax credits. We’ll explain how these work later in this article.

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Made in the USA

When the law was passed last year, the most controversial change to electric vehicle tax credit rules concerned where battery components are manufactured and assembled. Half of the loan — up to $3,750 — is tied to sourcing the battery’s critical minerals, which must be extracted or processed in the U.S. or a country with which it has a free trade agreement. For 2023, that amount must be at least 40 percent and increase by 10 percent per year through 2027, when at least 80 percent of these critical minerals must be extracted or processed in the United States or a Free Trade Partner nation.

The other $3,750 is tied to the proportion of battery components that were manufactured or assembled in North America. Again, this is an increasing percentage over time, starting at 50 percent of the value of the battery’s various components for 2023, 60 percent for 2024-2025, 70 percent in 2026, and then increasing by 10 percent per year through 2029, when the entire value of battery components must be manufactured or assembled in North America.

In addition, some conditions mean that from 2024 some vehicles will be excluded from credit if they contain battery components from a foreign company of concern.

Wait a minute, I’ve got an update

Although required by law, the IRS does not currently enforce it. Domestic procurement and value requirements are difficult to calculate, and in late December the US Treasury Department said it would not have guidance on battery minerals and component procurement until March.

By then at least, all qualifying clean vehicles should qualify for the full $7,500 credit, but which ones qualify?

The year 2023 is just a week old today.

With hopeful hearts we exchanged wishes for health, happiness and prosperity.

The stage curtain for 2022 has fallen, leaving joy and sorrow behind to welcome the new year with pounding hearts.

Hoping, always hoping…

But where does this exaggerated hope for better days come from?

As if the world would change. So the year 2023 would enchant us as if by magic?

As if, struck by grace, we live in joy?

Unless we are blinded by this belief in suffering humanity, we assume that 2023 could not be any worse than the ones before.

How ? Is there anything new under the sun?

Our young year 2023 rolls on the rails of the previous one.

The majority of people on the planet live under dictatorial regimes.

Our democracies are faltering in the face of the power of social networks, which bombard us with abbreviated information and full of false propaganda.

We are swimming in a sea of ​​”alternative truths and facts”.

Because Facebook and Twitter aren’t just used to share our photos of kittens, well-watered meals and vacations in the sun.

Elon Musk and Mark Zuckerberg serving the soup to the powerful who manipulate us… Frightening apostles.

It takes more than wishful thinking to lead us to the light.

Enough poopers played!

I forbid us to give up hope.

Let’s strive for a better world against all odds. Beginning with ours in Quebec, we boldly defend our language, our culture, and the values ​​we hold dear.

I offer you my best wishes for 2023.

Yesterday the Epiphany was celebrated according to a Christian tradition that has its origins in the East.

We eat Galette des Rois, hoping not to lose a crown by biting into the bean.

Let’s hope for less little kings and more pancakes in 2023!

SYLMAR, LOS ANGELES (KABC) – Many Southern California natural gas bills are suddenly becoming more expensive.

SoCal Gas has already warned customers: ‘January bills are likely to be shockingly high’

Lauren Davis is one of those shocked customers.

When she opened up her family’s gas bill this month, she found it was almost 25% higher than expected.

“I opened the bill and it was $330 and the first thing was, ‘What’s the temperature in our house?'” Davis said.

After taking a closer look, Davis found that she was actually using less gas this year than she did in the same period last year.

But the cost of natural gas stocks nearly doubled, resulting in more cash out of their pockets.

“For a colder house, less gas is being used and it’s crazy,” Davis said.

When SoCal Gas warned customers about the expected surge in a website message in late December, the company said natural gas market prices in the west more than doubled between December and January.

According to the US Energy Information Administration, the reasons for the price increase in natural gas included the following factors:

SoCalGas announced Friday that it has contributed $1 million to its gas relief fund, which provides one-time grants of $100 to qualifying applicants.

Davis said she doesn’t meet the income requirements. Instead, she had to draw on her family’s food budget. She worries about those with less flexibility, like her elderly neighbor.

“I can live in 66 (degrees). She can not. She’s on oxygen, she can’t live into 66 and they are actually looking for a roommate. That’s the answer,” Davis said, adding, “Having a 94-year-old gets a roommate?”

Among the tips SoCalGas gave to reduce natural gas usage was to avoid using it where it isn’t needed, such as around the house.

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Since 2019, airline customers in Canada are to be protected by a charter. Minister Marc Garneau was quite proud, when said charter was adopted, to go on his rounds of interviews to explain to us that there would be a ‘before’ and an ‘after’.

Delays, cancellations, lost luggage, the citizen who is the victim of a breakdown in the service offered should be able to be compensated. The reasonable compensation scales established by the government would guarantee compensation in proportion to the inconvenience suffered.

If they believed in the promises of this charter, the thousands of travelers who have gone through hell over the holiday season will likely fall from above. And I assume cases of force majeure. When the weather prevents a safe flight, we understand that aircraft must remain grounded and that companies cannot be held responsible.

sieve charter

The list of reasons airlines use to refuse to pay compensation makes Travelers Charter a laughing stock. First, airline lobbyists have successfully negotiated a good list of exemptions that gives them a way out. Then companies unashamedly stretched the rubber band in interpreting those exceptions.

As a result, consumers in Canada are not much better protected. Our charter certainly has nothing to do with the protection that European travelers enjoy. Although our plane tickets cost significantly more than in Europe.

The most interesting example, which is also being challenged in a class action lawsuit in court, is the use of the security argument. If a company doesn’t have all the necessary rest time one morning, the flight must be canceled out of prudence. Safety first. So far, companies seem to have gotten away with this argument.

Still, it is quite absurd to put understaffing (business management) and storm (force majeure) in the same category.

My case

I experienced the Travelers Charter myself in the summer of 2021. Travel with a friend, arranged at short notice: five days of golf on the incomparable courses of Prince Edward Island. A flight to Charlottetown on Air Canada.

On the day of departure, we arrive at Trudeau Airport at dawn. Rumor has it that the pilot or co-pilot did not return. flight cancelled. At first we hoped and believed that the flight would resume later in the day. no Morning ? No place. Next available spots: Day four of our five day vacation. water travel.

The only solution was to cancel the trip entirely and fight for refunds on accommodation and golf reservations.

I made the sad discovery that even in such an obvious case the Charter did not protect me. To compensate for the damage, the airline generously offered me a travel credit…on Air Canada Wings!

Fate Therapeutics Inc. FATE, -61.45%, plunged 56.8% in premarket trading, putting it on course for a one-day sell-off to record highs after the biopharmaceutical company announced ending its collaboration with Janssen Biotech Inc. and had announced job cuts. The company said it had rejected Janssen’s proposal to continue the collaboration on “revised terms”. The company added that it will reduce its workforce to approximately 220 employees, which translates to a workforce of 279 as of December 31, 2020, according to the company’s latest annual report. The job cuts came as the company decided to stop developing a number of “natural killer” (NK) cell programs for cancer treatments. Fate said it ended December with $475 million in cash, giving it ample resources through 2025. The company’s news prompted no fewer than seven of the 24 analysts polled by FactSet to downgrade the stock and 12 analysts to lower their price targets. The average target is now $22.40, according to FactSet, up from $59.15 at the end of December. The stock, which is on course to open during regular trading hours at its lowest price since December 2017, is already down 52.6% in the past three months to Thursday, while the iShares Biotechnology ETF IBB +1.00% increased by 7.8%. and the S&P 500 SPX, +2.28% is up 1.7%.