The San Francisco 49ers look to extend their regular-season winning streak to 13 games on Thursday night against the New York Giants, but they will be without one of their best wide receivers in the process. According to ESPNBrandon Aiyuk is not expected to play in Week 3 due to his shoulder injury.
Aiyuk is officially listed as questionable as he did not practice on Monday and has limited participation on Tuesday and Wednesday. The fifth-year wideout is off to a good start, catching 11 passes for 172 yards and two touchdowns in the first two games of the regular season. Aiyuk currently ranks 12th in receiving yards and second in receiving touchdowns.
The 49ers are big favorites over the Giants, who are also missing an important offensive weapon in running back Saquon Barkley. San Francisco is the first double-digit favorite of the 2023 NFL season as they lead by 10.5 points as of Thursday night, according to Caesars Sportsbook.
San Francisco has scored 30 points in five straight games, which is the longest streak in team history. With Christian McCaffrey, Deebo Samuel and George Kittle, quarterback Brock Purdy has no shortage of offensive weapons. As for who could carry the load at wideout in this matchup, Jauan Jennings, Ray-Ray McCloud III and Ronnie Bell should get more reps.