After the upset of defending champion TCU in the season opener, all eyes will be on Deion Sanders’ Colorado Buffaloes in the Week 2 college football schedule. The Buffs make their home debut against Nebraska, with both programs having had lean years of late after winning a combined eight national titles in the 1990s. With the Cornhuskers coming off a season-opening loss and Colorado led by Heisman hopefuls Shedeur Sanders and Travis Hunter, the Buffaloes are 3-point favorites in the Week 2 college football series, according to the SportsLine consensus.
Another cross-conference showdown this weekend is Iowa’s Cy-Hawk Trophy battle against Iowa State. The Hawkeyes are a 4-point favorite in the latest Week 2 college football odds, although Iowa State ended Iowa’s six-game winning streak in the series last year. Before you make any college football picks for this or any other game, be sure to check out the latest college football predictions from SportsLine’s trusted model.
The SportsLine projection model simulates every FBS college football game 10,000 times. The proprietary computer model is off to a fast 4-2 start on top-rated college football picks this season. Since its inception, it has generated an impressive profit of more than $2,500 for $100 players with its top-rated college football picks against the spread. Everyone who has pursued it has achieved tremendous success.
Now it has turned its attention to the latest college football odds for Week 2, setting picks for every FBS matchup. Head here to see each selection.
The best college football predictions for Week 2
One of the college football picks the model recommends for Saturday: Cincinnati (+8) easily covers away against Pittsburgh at kickoff at 6:30 p.m. ET. Both programs have completed nine-to-four seasons in 2022 and have posted overwhelming Week 1 wins over FCS schools. They also each have well-traveled sixth-graders at QB, as both Cincinnati’s Emory Jones and Pitt’s Phil Jurkovec are at their third school. However, Jones’ playing ability and Jurkovec’s carelessness with the football separate the two.
Jones scored seven total touchdowns (five passing, two rushing) in the Week 1 win over Eastern Kentucky, showcasing his dynamism with his arms and legs. He also protects the ball and has made just seven errors in his career, while Jurkovec is one of the most turnover-producing players in college football. The Pitt QB has 17 career interceptions and 16 career fumbles, despite having essentially the same number of snaps under center as Jones.
With two evenly matched teams on paper, the difference often lies in the most important position on the field, giving Cincy the advantage. The SportsLine model has Jurkovec committing more turnovers than Jones, and that allows the Bearcats (+8) to cover 70% of simulations.
Another prediction: No. 4 Alabama cruises to a blowout win as a 7-point home favorite against No. 11 Texas on Saturday at 7:00 p.m. ET. Bama quarterback Jalen Milroe brings a different dimension to the Tide offense with his running ability not seen since Jalen Hurts in Tuscaloosa. Last week, he became the first quarterback in Alabama history to pass for three touchdowns and score two scores in the same game.
Texas has its own star quarterback in Quinn Ewers, but he has had some issues along the way. Ewers’ career completion percentage is just 48.5% in away games, compared to 63.1% in home/neutral venue games. Playing in front of a hostile Alabama home crowd is only made worse by the mental advantage for Bama that comes with having Nick Saban on the sidelines. Texas went undefeated in the first eight head-to-head meetings between these teams, but Bama has won both meetings since Saban became head coach. Taking these factors into account, the model projects Alabama to win by double digits and cover (-7) well over 60% of the time. See which other teams like the model here.
How to make college football picks for Week 2
The model has also determined who will win and cover in every other FBS matchup in Week 2, and it calls for multiple underdogs to win outright. Only at SportsLine can you get every pick for every game.
So which college football picks can you make with confidence and which underdogs will win outright? Check out the latest college football odds below, then visit SportsLine to see which teams are winning and covering the spread, all with a proven computer model that has returned more than $2,500 in profits since its inception has, and find out.
College football odds for the top games of Week 2
Complete college football picks, odds and predictions for Week 2 can be found here
Saturday September 9th
Vanderbilt at Wake Forest (-11.5, 58.5)
Ball State at Georgia (-42, 53)
Notre Dame at NC State (+7.5, 50)
Utah at Baylor (+6, 50.5)
Nebraska at Colorado (-3, 58.5)
Texas A&M at Miami (FL) (+4, 49)
Iowa at Iowa State (+4, 36.5)
Ole Miss at Tulane (+6, 62.5)
Cincinnati at Pittsburgh (-8, 48.5)
Texas at Alabama (-7, 56.5)
Oregon at Texas Tech (+6.5, 67)
Wisconsin at Washington State (+4, 54.5)
Oklahoma State at Arizona State (+3.5, 53)