Ways of manufacturing a male contraceptive have been studied for many years. Although several drugs were presented, none received approval, so they were discontinued.
But that didn’t end the polls; on the other hand. Scientists specializing in the field of contraceptives continued to look for ways to develop a drug that could do this prevent fertilization without male sterility.
Most drugs aren’t approved because they alter the production of testosterone, the male hormone. But the latest discovery appears to be changing the situation.
According to a study published in the digital journal Nature, the new male contraceptive has the expected effect without the need for hormones.
The drug works by removing the mobility of sperm, which are “numbed” by the use of the drug. According to the team responsible for making the drug, the effects kick in about an hour after ingestion.
In addition, the effect reverses after a few hours. That is, men using the drug do not need to take the drug continuously, it is only necessary to take it a few hours before the sexual act.
If there are no hormones, how does it work?
If you asked the question above, you know that this product works on the basis of a protein called sAC, or soluble adenylyl cyclase. Since it is not a hormone solution, this medicine does not cause any side effects related to the production of male hormones.
The drug is still in the test phase and has so far only been given the name TDI11861. The first tests were performed on laboratorybred mice when the effects presented by the research were confirmed. In animals, sperm production had lost the ability to move.
According to the data presented, the motion loss effect remained active for about three hours. Thus, gamete movement returned to normal 24 hours later. Therefore, unlike female contraceptives, which take an average of three months to wear off, this one lasts for hours.
According to the team responsible, tests began soon on rabbits and only later on humans. If successful in human trials, this new drug will allow men to make decisions about their fertility on a daily basis.